The Umbilical Cord Blood Transplant Unit at Yashoda hospital consistently aims at providing quality health assistance to improve the lives of patients requiring treatment for blood-related disorders.
The comprehensive patient care we provide is on par with international guidelines. We follow a patient-centric treatment plan using cutting-edge technologies, innovative techniques and methodologies.
What Is Umbilical Cord Blood Transplantation?
Umbilical cord blood is one of the richest sources of stem cells and extensively utilized for transplantation. In this form of transplant, stems cells are reserved from umbilical cord blood. The source of umbilical cord blood is the umbilical cord retrieve after the birth of the baby. For future use in cord blood transplant, this cord blood is processed and frozen.
Although cord blood cells have fewer stem cells as compare to other transplants but hold a high tendency of growing more blood cells inside the body than those present in the bone marrow. The advantage of using Umbilical cord blood transplant is that the immune cells in cord blood are still "naive". This means they are not yet active in attacking other cells and are less likely to attack the tissues of the transplant recipient. Therefore, they do not necessarily have to be a close match.
What Are The Indicators For This Transplant?
There are numerous serious health conditions which require Umbilical cord blood transplant as a cure. Such illnesses include:
What Is The Procedure Of The Transplant?
Umbilical cord blood transplantation is a process to replace maligned cells with new cells lining and help in replacing maligned cells or invigorate the system of new cells production.
Step 1: Pre-transplant Process: To ensure their general health and the status of the current medical condition, a patient has to take a series of Pre-transplant tests and procedures. This process of analysis may take several days.
Step 2: Conditioning Process: After the completion of the medical evaluation, a patient undergoes the conditioning process. This process involves the use of either chemotherapy or radiation therapy or a combination to:
Step 3: Umbilical cord blood Transplant: For the cytotoxic treatment, the patient has to undergo the transplantation of the harvested where processed cells are put back into the patient's body, through a central venous catheter. These cells then move through the bloodstream into the bones' places, where they tend to create new bone marrow. The transplant provides a patient's body with a tendency to create new blood cells in a process, which is known as engraftment.
Step 4: Engraftment: The patient is kept under close monitoring for the sign of the growth of new stem cells along with supportive care.
Step 5: The Patient undergoes Post Engraftment monitoring and continuation of immunosuppression
What Are The Precautions One Must Take Before And After The Transplant?
A patient must take care of some of the essential precautions before and after the transplantation process, which includes:
Before the Transplantation:
After the Transplantation:
Are There Any Risk Complications Involved?
Usually, a patient receives high-intensity doses of chemotherapy or radiation therapy before a transplant, resulting in complications such as:
Other complications due to transplant include:
Studies have proved that there are fewer complications in Umbilical cord blood transplantation as compared to the different type of transplants. However, it is the most beneficial type of transplant, as there is no need to match the cord blood closer to the patient's blood. Therefore, it serves as an option for a patient with uncommon tissue types.